Ontology highlight
ABSTRACT:
SUBMITTER: Musci TJ
PROVIDER: S-EPMC54956 | biostudies-other | 1990 Nov
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19901101 21
Recent evidence suggests that fibroblast growth factor (FGF) is a primary mesoderm inducer in Xenopus development. We have isolated a full-length cDNA clone for the Xenopus FGF receptor. Like other FGF receptors, the Xenopus homolog is a membrane-spanning protein with a split intracellular tyrosine kinase domain. The Xenopus FGF receptor mRNA is present as a maternal message whose levels are constant through early development. There is no specific regional localization of the transcript by analy ...[more]