The stratified syncytium of the vertebrate lens.
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ABSTRACT:
SUBMITTER: Shi Y
PROVIDER: S-EPMC2680101 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Publications
The stratified syncytium of the vertebrate lens.
Shi Yanrong Y Barton Kelly K De Maria Alicia A Petrash J Mark JM Shiels Alan A Bassnett Steven S
Journal of cell science 20090428 Pt 10
The fusion of cells to generate syncytial tissues is a crucial event in the development of many organisms. In the lens of the vertebrate eye, proteins and other macromolecules diffuse from cell to cell via the large molecule diffusion pathway (LMDP). We used the tamoxifen-induced expression of GFP to investigate the nature and role of the LMDP in living, intact lenses. Our data indicate that the LMPD preferentially connects cells lying within a stratum of the lens cortex and that formation of th ...[more]
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