Ontology highlight
ABSTRACT:
SUBMITTER: Connelly PW
PROVIDER: S-EPMC2681404 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Connelly Philip W PW Zinman Bernard B Maguire Graham F GF Mamakeesick Mary M Harris Stewart B SB Hegele Robert A RA Retnakaran Ravi R Hanley Anthony J G AJ
Journal of lipid research 20090118 6
Paraoxonase 1 (PON1) has been reported to be associated with proteinuria in subjects with type 2 diabetes mellitus (T2DM). Plasma cystatin C is more accurate than creatinine for identifying stage 3 kidney disease in T2DM. We tested the hypothesis that PON1 and cystatin C would be associated in T2DM subjects from an Aboriginal Canadian community, who are at high risk for the development of nephropathy. PON1 A(-162)G and PON2 Ala148Gly genotypes, cystatin C, HbA1c, high density lipoprotein cholest ...[more]