Ontology highlight
ABSTRACT:
SUBMITTER: Wydau S
PROVIDER: S-EPMC2682858 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Wydau Sandra S van der Rest Guillaume G Aubard Caroline C Plateau Pierre P Blanquet Sylvain S
The Journal of biological chemistry 20090330 21
Several l-aminoacyl-tRNA synthetases can transfer a d-amino acid onto their cognate tRNA(s). This harmful reaction is counteracted by the enzyme d-aminoacyl-tRNA deacylase. Two distinct deacylases were already identified in bacteria (DTD1) and in archaea (DTD2), respectively. Evidence was given that DTD1 homologs also exist in nearly all eukaryotes, whereas DTD2 homologs occur in plants. On the other hand, several bacteria, including most cyanobacteria, lack genes encoding a DTD1 homolog. Here w ...[more]