Ontology highlight
ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC4201824 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Chen Xinguo X Sim Soyeong S Wurtmann Elisabeth J EJ Feke Ann A Wolin Sandra L SL
RNA (New York, N.Y.) 20140917 11
Many bacteria encode an ortholog of the Ro60 autoantigen, a ring-shaped protein that is bound in animal cells to noncoding RNAs (ncRNAs) called Y RNAs. Studies in Deinococcus radiodurans revealed that Y RNA tethers Ro60 to polynucleotide phosphorylase, specializing this exoribonuclease for structured RNA degradation. Although Ro60 orthologs are present in a wide range of bacteria, Y RNAs have been detected in only two species, making it unclear whether these ncRNAs are common Ro60 partners in ba ...[more]