Ontology highlight
ABSTRACT:
SUBMITTER: Jain N
PROVIDER: S-EPMC2686079 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Biochemical and biophysical research communications 20081225 2
HflX is a GTP binding protein of unknown function. Based on the presence of the hflX gene in hflA operon, HflX was believed to be involved in the lytic-lysogenic decision during phage infection in Escherichia coli. We find that E. coli HflX binds 16S and 23S rRNA - the RNA components of 30S and 50S ribosomal subunits. Here, using purified ribosomal subunits, we show that HflX specifically interacts with the 50S. This finding is in line with the homology of HflX to GTPases involved in ribosome bi ...[more]