SDR: a database of predicted specificity-determining residues in proteins.
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ABSTRACT:
SUBMITTER: Donald JE
PROVIDER: S-EPMC2686543 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Publications
SDR: a database of predicted specificity-determining residues in proteins.
Donald Jason E JE Shakhnovich Eugene I EI
Nucleic acids research 20081016 Database issue
The specificity-determining residue database (SDR database) presents residue positions where mutations are predicted to have changed protein function in large protein families. Because the database pre-calculates predictions on existing protein sequence alignments, users can quickly find the predictions by selecting the appropriate protein family or searching by protein sequence. Predictions can be used to guide mutagenesis or to gain a better understanding of specificity changes in a protein fa ...[more]
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