Ontology highlight
ABSTRACT:
SUBMITTER: Kristiansson K
PROVIDER: S-EPMC2687549 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Kristiansson Kati K Ilveskoski Erkki E Lehtimäki Terho T Peltonen Leena L Perola Markus M Karhunen Pekka J PJ
Arteriosclerosis, thrombosis, and vascular biology 20080214 5
<h4>Objective</h4>USF1 regulates the transcription of more than 40 cardiovascular related genes and is well established as a gene associated with familial combined hyperlipidemia, a condition increasing the risk for coronary heart disease. No detailed data, however, exists on the impact of this gene to the critical outcome at the tissue level: different types of atherosclerotic lesions.<h4>Methods and results</h4>We analyzed the USF1 in 2 autopsy series of altogether 700 middle-aged men (the Hel ...[more]