Ontology highlight
ABSTRACT:
SUBMITTER: Schunkert H
PROVIDER: S-EPMC2689930 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Schunkert Heribert H Götz Anika A Braund Peter P McGinnis Ralph R Tregouet David-Alexandre DA Mangino Massimo M Linsel-Nitschke Patrick P Cambien Francois F Hengstenberg Christian C Stark Klaus K Blankenberg Stefan S Tiret Laurence L Ducimetiere Pierre P Keniry Andrew A Ghori Mohammed J R MJ Schreiber Stefan S El Mokhtari Nour Eddine NE Hall Alistair S AS Dixon Richard J RJ Goodall Alison H AH Liptau Henrike H Pollard Helen H Schwarz Daniel F DF Hothorn Ludwig A LA Wichmann H-Erich HE König Inke R IR Fischer Marcus M Meisinger Christa C Ouwehand Willem W Deloukas Panos P Thompson John R JR Erdmann Jeanette J Ziegler Andreas A Samani Nilesh J NJ
Circulation 20080324 13
<h4>Background</h4>Recently, genome-wide association studies identified variants on chromosome 9p21.3 as affecting the risk of coronary artery disease (CAD). We investigated the association of this locus with CAD in 7 case-control studies and undertook a meta-analysis.<h4>Methods and results</h4>A single-nucleotide polymorphism (SNP), rs1333049, representing the 9p21.3 locus, was genotyped in 7 case-control studies involving a total of 4645 patients with myocardial infarction or CAD and 5177 con ...[more]