Ontology highlight
ABSTRACT:
SUBMITTER: Hawn TR
PROVIDER: S-EPMC2696082 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Hawn Thomas R TR Scholes Delia D Li Shuying S SS Wang Hongwei H Yang Yin Y Roberts Pacita L PL Stapleton Ann E AE Janer Marta M Aderem Alan A Stamm Walter E WE Zhao Lue Ping LP Hooton Thomas M TM
PloS one 20090622 6
<h4>Background</h4>Although behavioral risk factors are strongly associated with urinary tract infection (UTI) risk, the role of genetics in acquiring this disease is poorly understood.<h4>Methodology/principal findings</h4>To test the hypothesis that polymorphisms in Toll-like receptor (TLR) pathway genes are associated with susceptibility to UTIs, we conducted a population-based case-control study of women ages 18-49 years. We examined DNA variants in 9 TLR pathway genes in 431 recurrent cysti ...[more]