Ontology highlight
ABSTRACT:
SUBMITTER: Demuro A
PROVIDER: S-EPMC2701662 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Cell calcium 20070822 4
Elementary events such as puffs and sparks are cytosolic microdomains of Ca2+ from which cellular Ca2+ signals are constructed. Because of the tight localization and fast kinetics of elementary events, imaging studies have been hindered by instrumental limitations of confocal and deconvolution fluorescence microscopy which necessitate compromises between spatial and temporal resolution. Here, we describe a novel, yet simple 'multi-focal' fluorescence microscopy system that employs three high-spe ...[more]