Emergence of quinolone-resistant Bordetella pertussis in Japan.
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ABSTRACT:
SUBMITTER: Ohtsuka M
PROVIDER: S-EPMC2704657 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Publications
Emergence of quinolone-resistant Bordetella pertussis in Japan.
Ohtsuka Masayuki M Kikuchi Ken K Shimizu Kenichiro K Takahashi Namiko N Ono Yuka Y Sasaki Takashi T Hiramatsu Keiichi K
Antimicrobial agents and chemotherapy 20090504 7
Six Bordetella pertussis strains isolated from children in Japan from 2004 to 2006 showed high-level resistance to nalidixic acid (NAL; MIC, >256 microg/ml) and decreased susceptibilities to fluoroquinolones. All of the NAL-resistant strains had the same D87G mutation in gyrA. ...[more]
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