Ontology highlight
ABSTRACT:
SUBMITTER: Sheffler W
PROVIDER: S-EPMC2708028 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20090101 1
We present a novel method called RosettaHoles for visual and quantitative assessment of underpacking in the protein core. RosettaHoles generates a set of spherical cavity balls that fill the empty volume between atoms in the protein interior. For visualization, the cavity balls are aggregated into contiguous overlapping clusters and small cavities are discarded, leaving an uncluttered representation of the unfilled regions of space in a structure. For quantitative analysis, the cavity ball data ...[more]