Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific.
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ABSTRACT:
SUBMITTER: Castellanos E
PROVIDER: S-EPMC2708469 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
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Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific.
Castellanos Elena E Aranaz Alicia A de Juan Lucia L Alvarez Julio J Rodríguez Sabrina S Romero Beatriz B Bezos Javier J Stevenson Karen K Mateos Ana A Domínguez Lucas L
Journal of clinical microbiology 20090513 7
Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes. ...[more]
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