Ontology highlight
ABSTRACT:
SUBMITTER: Shuto E
PROVIDER: S-EPMC2709683 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Shuto Emi E Taketani Yutaka Y Tanaka Rieko R Harada Nagakatsu N Isshiki Masashi M Sato Minako M Nashiki Kunitaka K Amo Kikuko K Yamamoto Hironori H Higashi Yukihito Y Nakaya Yutaka Y Takeda Eiji E
Journal of the American Society of Nephrology : JASN 20090430 7
Excessive dietary phosphorus may increase cardiovascular risk in healthy individuals as well as in patients with chronic kidney disease, but the mechanisms underlying this risk are not completely understood. To determine whether postprandial hyperphosphatemia may promote endothelial dysfunction, we investigated the acute effect of phosphorus loading on endothelial function in vitro and in vivo. Exposing bovine aortic endothelial cells to a phosphorus load increased production of reactive oxygen ...[more]