Ontology highlight
ABSTRACT:
SUBMITTER: Imoukhuede PI
PROVIDER: S-EPMC2711277 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Biophysical journal 20090401 7
A high density of neurotransmitter transporters on axons and presynaptic boutons is required for the efficient clearance of neurotransmitters from the synapse. Therefore, regulators of transporter trafficking (insertion, retrieval, and confinement) can play an important role in maintaining the transporter density necessary for effective function. We determined the interactions that confine GAT1 at the membrane by investigating the lateral mobility of GAT1-yellow fluorescent protein-8 (YFP8) expr ...[more]