Ontology highlight
ABSTRACT:
SUBMITTER: Sagara I
PROVIDER: S-EPMC2713037 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Vaccine 20090325 23
A double blind, randomized, controlled Phase 2 clinical trial was conducted to assess the safety, immunogenicity, and biologic impact of the vaccine candidate Apical Membrane Antigen 1-Combination 1 (AMA1-C1), adjuvanted with Alhydrogel. Participants were healthy children 2-3 years old living in or near the village of Bancoumana, Mali. A total of 300 children received either the study vaccine or the comparator. No impact of vaccination was seen on the primary endpoint, the frequency of parasitem ...[more]