Ontology highlight
ABSTRACT:
SUBMITTER: Zhou Z
PROVIDER: S-EPMC2715959 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Zhou Zhifeng Z Zhu Guanshan G Hariri Ahmad R AR Enoch Mary-Anne MA Scott David D Sinha Rajita R Virkkunen Matti M Mash Deborah C DC Lipsky Robert H RH Hu Xian-Zhang XZ Hodgkinson Colin A CA Xu Ke K Buzas Beata B Yuan Qiaoping Q Shen Pei-Hong PH Ferrell Robert E RE Manuck Stephen B SB Brown Sarah M SM Hauger Richard L RL Stohler Christian S CS Zubieta Jon-Kar JK Goldman David D
Nature 20080402 7190
Understanding inter-individual differences in stress response requires the explanation of genetic influences at multiple phenotypic levels, including complex behaviours and the metabolic responses of brain regions to emotional stimuli. Neuropeptide Y (NPY) is anxiolytic and its release is induced by stress. NPY is abundantly expressed in regions of the limbic system that are implicated in arousal and in the assignment of emotional valences to stimuli and memories. Here we show that haplotype-dri ...[more]