Ontology highlight
ABSTRACT:
SUBMITTER: Potier M
PROVIDER: S-EPMC2717784 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Potier Marie M Gonzalez José C JC Motiani Rajender K RK Abdullaev Iskandar F IF Bisaillon Jonathan M JM Singer Harold A HA Trebak Mohamed M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090413 8
The identity of store-operated calcium (Ca(2+)) entry (SOCE) channels in vascular smooth muscle cells (VSMCs) remains a highly contentious issue. Whereas previous studies have suggested that SOCE in VSMCs is mediated by the nonselective transient receptor potential canonical (TRPC) 1 protein, the identification of STIM1 and Orai1 as essential components of I(CRAC), a highly Ca(2+)-selective SOCE current in leukocytes, has challenged that view. Here we show that cultured proliferative migratory V ...[more]