Preparation of the Major Urinary Metabolite of (-)-Prostaglandin E(2).
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ABSTRACT:
SUBMITTER: Taber DF
PROVIDER: S-EPMC2719863 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
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Preparation of the Major Urinary Metabolite of (-)-Prostaglandin E(2).
Taber Douglass F DF Gu Peiming P
Tetrahedron 20090801 31
The best way to measure whole body production of the locally acting hormone prostaglandin E(2) (PGE(2)) is to assess the accumulation of the major urinary metabolite, PGE(2) U (M). A practical preparation of this delicate diacid is described. This synthetic PGE(2)U(M) will enable production of the antibodies that will be used to quantify this key metabolite. ...[more]
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