Ontology highlight
ABSTRACT:
SUBMITTER: Chang BL
PROVIDER: S-EPMC2722195 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Chang Bao-Li BL Cramer Scott D SD Wiklund Fredrik F Isaacs Sarah D SD Stevens Victoria L VL Sun Jielin J Smith Shelly S Pruett Kristen K Romero Lina M LM Wiley Kathleen E KE Kim Seong-Tae ST Zhu Yi Y Zhang Zheng Z Hsu Fang-Chi FC Turner Aubrey R AR Adolfsson Jan J Liu Wennuan W Kim Jin Woo JW Duggan David D Carpten John J Zheng S Lilly SL Rodriguez Carmen C Isaacs William B WB Grönberg Henrik H Xu Jianfeng J
Human molecular genetics 20090119 7
A single nucleotide polymorphism (SNP) at 10q11 (rs10993994) in the 5' region of the MSMB gene was recently implicated in prostate cancer risk in two genome-wide association studies. To identify possible causal variants in the region, we genotyped 16 tagging SNPs and imputed 29 additional SNPs in approximately 65 kb genomic region at 10q11 in a Swedish population-based case-control study (CAncer of the Prostate in Sweden), including 2899 cases and 1722 controls. We found evidence for two indepen ...[more]