Ontology highlight
ABSTRACT:
SUBMITTER: Wozniak MJ
PROVIDER: S-EPMC2723153 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Woźniak Marcin J MJ Bola Becky B Brownhill Kim K Yang Yen-Ching YC Levakova Vesselina V Allan Victoria J VJ
Journal of cell science 20090519 Pt 12
Generating the extended endoplasmic reticulum (ER) network depends on microtubules, which act as tracks for motor-driven ER tubule movement, generate the force to extend ER tubules by means of attachment to growing microtubule plus-ends and provide static attachment points. We have analysed ER dynamics in living VERO cells and find that most ER tubule extension is driven by microtubule motors. Surprisingly, we observe that approximately 50% of rapid ER tubule movements occur in the direction of ...[more]