Ontology highlight
ABSTRACT:
SUBMITTER: Zavaleta CL
PROVIDER: S-EPMC2726370 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Zavaleta Cristina L CL Smith Bryan R BR Walton Ian I Doering William W Davis Glenn G Shojaei Borzoyeh B Natan Michael J MJ Gambhir Sanjiv S SS
Proceedings of the National Academy of Sciences of the United States of America 20090728 32
Raman spectroscopy is a newly developed, noninvasive preclinical imaging technique that offers picomolar sensitivity and multiplexing capabilities to the field of molecular imaging. In this study, we demonstrate the ability of Raman spectroscopy to separate the spectral fingerprints of up to 10 different types of surface enhanced Raman scattering (SERS) nanoparticles in a living mouse after s.c. injection. Based on these spectral results, we simultaneously injected the five most intense and spec ...[more]