Ontology highlight
ABSTRACT:
SUBMITTER: Brill LM
PROVIDER: S-EPMC2726933 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Brill Laurence M LM Xiong Wen W Lee Ki-Bum KB Ficarro Scott B SB Crain Andrew A Xu Yue Y Terskikh Alexey A Snyder Evan Y EY Ding Sheng S
Cell stem cell 20090801 2
Protein phosphorylation, while critical to cellular behavior, has been undercharacterized in pluripotent cells. Therefore, we performed phosphoproteomic analyses of human embryonic stem cells (hESCs) and their differentiated derivatives. A total of 2546 phosphorylation sites were identified on 1602 phosphoproteins; 389 proteins contained more phosphorylation site identifications in undifferentiated hESCs, whereas 540 contained more such identifications in differentiated derivatives. Phosphoprote ...[more]