Ontology highlight
ABSTRACT:
SUBMITTER: Brady RC
PROVIDER: S-EPMC2730950 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Brady Rebecca C RC Treanor John J JJ Atmar Robert L RL Keitel Wendy A WA Edelman Robert R Chen Wilbur H WH Winokur Patricia P Belshe Robert R Graham Irene L IL Noah Diana Lee DL Guo Kuo K Hill Heather H
Vaccine 20090703 37
A total of 600 healthy adults > or =65 years were randomized to receive 2 vaccinations 1 month apart of a subvirion avian influenza A/H5N1 vaccine containing 3.75, 7.5, 15, or 45microg of hemagglutinin (HA) with or without aluminum hydroxide (AlOH). All formulations were safe. Groups given the vaccine with AlOH had more injection site discomfort. Dose-related increases in antibody responses were noted after the second vaccination. Antibody responses to the vaccine were not enhanced by AlOH at an ...[more]