Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC2731560 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Wang Li L Li Min M Dong Dandan D Bach Thanh-Huy L TH Sturdevant Daniel E DE Vuong Cuong C Otto Michael M Gao Qian Q
The Journal of infectious diseases 20080501 9
Biofilm-associated infection due to Staphylococcus epidermidis, the leading nosocomial pathogen, is a major problem for the public health system, but the regulation of this important phenotype is not completely understood. Using a highly discriminatory screening procedure for genes that influence biofilm formation, we identified the transcriptional regulator SarZ as a novel important determinant of biofilm formation and biofilm-associated infection, on the basis of the significant impact of sarZ ...[more]