Ontology highlight
ABSTRACT:
SUBMITTER: Sinnaeve PR
PROVIDER: S-EPMC2736586 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Sinnaeve Peter R PR Donahue Mark P MP Grass Peter P Seo David D Vonderscher Jacky J Chibout Salah-Dine SD Kraus William E WE Sketch Michael M Nelson Charlotte C Ginsburg Geoffrey S GS Goldschmidt-Clermont Pascal J PJ Granger Christopher B CB
PloS one 20090914 9
Systemic and local inflammation plays a prominent role in the pathogenesis of atherosclerotic coronary artery disease, but the relationship of whole blood gene expression changes with coronary disease remains unclear. We have investigated whether gene expression patterns in peripheral blood correlate with the severity of coronary disease and whether these patterns correlate with the extent of atherosclerosis in the vascular wall. Patients were selected according to their coronary artery disease ...[more]