Ontology highlight
ABSTRACT:
SUBMITTER: Geng Y
PROVIDER: S-EPMC2740330 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Nature nanotechnology 20070325 4
Interaction of spherical particles with cells and within animals has been studied extensively, but the effects of shape have received little attention. Here we use highly stable, polymer micelle assemblies known as filomicelles to compare the transport and trafficking of flexible filaments with spheres of similar chemistry. In rodents, filomicelles persisted in the circulation up to one week after intravenous injection. This is about ten times longer than their spherical counterparts and is more ...[more]