Ontology highlight
ABSTRACT:
SUBMITTER: Schmidt MR
PROVIDER: S-EPMC2741253 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Schmidt Michael R MR Maritzen Tanja T Kukhtina Viktoria V Higman Victoria A VA Doglio Laura L Barak Naomi N NN Strauss Holger H Oschkinat Hartmut H Dotti Carlos G CG Haucke Volker V
Proceedings of the National Academy of Sciences of the United States of America 20090821 36
Endosomes and endosomal vesicles (EVs) rapidly move along cytoskeletal filaments allowing them to exchange proteins and lipids between different endosomal compartments, lysosomes, the trans-Golgi network (TGN), and the plasma membrane. The precise mechanisms that connect membrane traffic between the TGN and perinuclear endosomal compartments with motor-protein driven transport have largely remained elusive. Here we show that Gadkin (also termed gamma-BAR), a peripheral membrane protein localized ...[more]