Ontology highlight
ABSTRACT:
SUBMITTER: Scharenberg AM
PROVIDER: S-EPMC2743935 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Nature reviews. Immunology 20071001 10
Alterations in the cytosolic concentration of calcium ions (Ca2+) transmit information that is crucial for the development and function of B cells. Cytosolic Ca2+ concentration is determined by a balance of active transport and gradient-driven Ca2+ fluxes, both of which are subject to the influence of multiple receptors and environmental sensing pathways. Recent advances in genomics have allowed for the compilation of an increasingly comprehensive list of Ca2+ transporters and channels expressed ...[more]