Ontology highlight
ABSTRACT:
SUBMITTER: McKinney SA
PROVIDER: S-EPMC2745648 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
McKinney Sean A SA Murphy Christopher S CS Hazelwood Kristin L KL Davidson Michael W MW Looger Loren L LL
Nature methods 20090125 2
Photoconvertible fluorescent proteins are potential tools for investigating dynamic processes in living cells and for emerging super-resolution microscopy techniques. Unfortunately, most probes in this class are hampered by oligomerization, small photon budgets or poor photostability. Here we report an EosFP variant that functions well in a broad range of protein fusions for dynamic investigations, exhibits high photostability and preserves the approximately 10-nm localization precision of its p ...[more]