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ABSTRACT:
SUBMITTER: Terwilliger TC
PROVIDER: S-EPMC2745886 | biostudies-literature | 2001 Dec
REPOSITORIES: biostudies-literature
Acta crystallographica. Section D, Biological crystallography 20011121 Pt 12
The likelihood-based approach to density modification [Terwilliger (2000), Acta Cryst. D56, 965-972] is extended to include the recognition of patterns of electron density. Once a region of electron density in a map is recognized as corresponding to a known structural element, the likelihood of the map is reformulated to include a term that reflects how closely the map agrees with the expected density for that structural element. This likelihood is combined with other aspects of the likelihood o ...[more]