Maximum-likelihood density modification.
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ABSTRACT:
SUBMITTER: Terwilliger TC
PROVIDER: S-EPMC2792768 | biostudies-literature | 2000 Aug
REPOSITORIES: biostudies-literature
Publications
Maximum-likelihood density modification.
Acta crystallographica. Section D, Biological crystallography 20000801 Pt 8
A likelihood-based approach to density modification is developed that can be applied to a wide variety of cases where some information about the electron density at various points in the unit cell is available. The key to the approach consists of developing likelihood functions that represent the probability that a particular value of electron density is consistent with prior expectations for the electron density at that point in the unit cell. These likelihood functions are then combined with l ...[more]
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