Ontology highlight
ABSTRACT:
SUBMITTER: Cullen SC
PROVIDER: S-EPMC2746454 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature
Organic letters 20080613 14
An intramolecular Stetter reaction of vinylphosphine oxides and vinylphosphonates has been developed. Treatment of an aldehyde with a nucleophilic N-heterocyclic carbene catalyst allows for addition of an acyl anion equivalent into a vinylphosphine oxide or vinylphosphonate Michael acceptor in yields up to 99% and ee values up to 96%. ...[more]