Ontology highlight
ABSTRACT:
SUBMITTER: Greenberg PL
PROVIDER: S-EPMC2746469 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Greenberg Peter L PL Sun Zhuoxin Z Miller Kenneth B KB Bennett John M JM Tallman Martin S MS Dewald Gordon G Paietta Elisabeth E van der Jagt Richard R Houston Jessie J Thomas Mary L ML Cella David D Rowe Jacob M JM
Blood 20090629 12
This phase 3 prospective randomized trial evaluated the efficacy and long-term safety of erythropoietin (EPO) with or without granulocyte colony-stimulating factor plus supportive care (SC; n = 53) versus SC alone (n = 57) for the treatment of anemic patients with lower-risk myelodysplastic syndromes. The response rates in the EPO versus SC alone arms were 36% versus 9.6%, respectively, at the initial treatment step, 47% in the EPO arm, including subsequent steps. Responding patients had signifi ...[more]