Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.
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ABSTRACT:
SUBMITTER: Wong HR
PROVIDER: S-EPMC2747356 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Publications
Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.
Wong Hector R HR Cvijanovich Natalie N Allen Geoffrey L GL Lin Richard R Anas Nick N Meyer Keith K Freishtat Robert J RJ Monaco Marie M Odoms Kelli K Sakthivel Bhuvaneswari B Shanley Thomas P TP
Critical care medicine 20090501 5
<h4>Objectives</h4>To advance our biological understanding of pediatric septic shock, we measured the genome-level expression profiles of critically ill children representing the systemic inflammatory response syndrome (SIRS), sepsis, and septic shock spectrum.<h4>Design</h4>Prospective observational study involving microarray-based bioinformatics.<h4>Setting</h4>Multiple pediatric intensive care units in the United States.<h4>Patients</h4>Children <or=10 years of age: 18 normal controls, 22 mee ...[more]
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