Ontology highlight
ABSTRACT:
SUBMITTER: Goyos A
PROVIDER: S-EPMC2749489 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Frontiers in bioscience (Landmark edition) 20090101 1
Despite intense study, the role of the immune system in detecting (immunosurveillance), controlling and remodeling (immunoediting) neoplasia remains elusive. We present here a comparative view of the complex interactions between neoplasia and the host immune system. We provide evidence, in the amphibian Xenopus laevis, consistent with an evolutionarily conserved and crucial role of the immune system in controlling neoplasia, which involves a striking variety of anti-tumoral immune effectors incl ...[more]