Expression of stem cell pluripotency factors during regeneration in newts.
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ABSTRACT:
SUBMITTER: Maki N
PROVIDER: S-EPMC2749736 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Publications
Expression of stem cell pluripotency factors during regeneration in newts.
Maki Nobuyasu N Suetsugu-Maki Rinako R Tarui Hiroshi H Agata Kiyokazu K Del Rio-Tsonis Katia K Tsonis Panagiotis A PA
Developmental dynamics : an official publication of the American Association of Anatomists 20090601 6
In this study, we present data indicating that mammalian stem cell pluripotency-inducing factors are expressed during lens and limb regeneration in newts. The apparent expression even in intact tissues and the ensued regulation during regeneration raises the possibility that these factors might regulate tissue-specific reprogramming and regeneration. Furthermore, these factors should enable us to understand the similarities and differences between animal regeneration in the newt and stem cell st ...[more]
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