Ontology highlight
ABSTRACT:
SUBMITTER: Sun YS
PROVIDER: S-EPMC2751602 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Sun Y S YS Landry J P JP Fei Y Y YY Zhu X D XD Luo J T JT Wang X B XB Lam K S KS
Analytical chemistry 20090701 13
We explored two macromolecular scaffolds, bovine serum albumin (BSA) and polyvinyl alcohol (PVA), as chemically complementary platforms for immobilizing small molecule compounds on functionalized glass slides. We conjugated biotin molecules to BSA and amine-derivatized PVA and subsequently immobilized the conjugates on epoxy-functionalized glass slides through reaction of free amine residues on BSA and PVA with surface-bound epoxy groups. We studied binding reactions of such immobilized small mo ...[more]