Ontology highlight
ABSTRACT:
SUBMITTER: Sardiu ME
PROVIDER: S-EPMC2751824 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Sardiu Mihaela E ME Gilmore Joshua M JM Carrozza Michael J MJ Li Bing B Workman Jerry L JL Florens Laurence L Washburn Michael P MP
PloS one 20091006 10
Protein complexes are key molecular machines executing a variety of essential cellular processes. Despite the availability of genome-wide protein-protein interaction studies, determining the connectivity between proteins within a complex remains a major challenge. Here we demonstrate a method that is able to predict the relationship of proteins within a stable protein complex. We employed a combination of computational approaches and a systematic collection of quantitative proteomics data from w ...[more]