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Substituent effects on thermal decolorization rates of bisbenzospiropyrans.

ABSTRACT: [reaction: see text] A novel application of photochromic molecules is to mimic physiological oscillatory calcium signals by reversibly binding and releasing calcium ions in response to light. Substituent changes on the largely unexplored photochromic bisbenzospiropyran scaffold led to significant changes in thermal fading rates in several organic solvents. Excellent correlations have been found between fading rates and empirical Hammett constants as well as calculated ground-state energies. These correlations can be used to improve scaffold design.

SUBMITTER: Lu NT

PROVIDER: S-EPMC2752390 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature

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Substituent effects on thermal decolorization rates of bisbenzospiropyrans.

Lu Nina T NT Nguyen Vi N VN Kumar Satish S McCurdy Alison A

The Journal of organic chemistry 20051001 22

[reaction: see text] A novel application of photochromic molecules is to mimic physiological oscillatory calcium signals by reversibly binding and releasing calcium ions in response to light. Substituent changes on the largely unexplored photochromic bisbenzospiropyran scaffold led to significant changes in thermal fading rates in several organic solvents. Excellent correlations have been found between fading rates and empirical Hammett constants as well as calculated ground-state energies. Thes ...[more]

PMID: 16238356

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