Ontology highlight
ABSTRACT:
SUBMITTER: Morahan G
PROVIDER: S-EPMC2753859 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Morahan G G Mehta M M McKinnon E E James I I
Diabetes, obesity & metabolism 20090201
<h4>Aim</h4>Type 1 diabetes susceptibility is influenced by a number of genes, of which those with the strongest effects map to the human leucocyte antigen (HLA) complex. Evidence for linkage of non-HLA genes in several affected sib-pair analyses was increased if the HLA or gender status of the sibs was considered independently. We investigated whether linkage status at the HLA complex differentially affected transmission of alleles to sibs depending on their HLA or gender linkage status.<h4>Met ...[more]