SUMO takes control of a ubiquitin-specific protease.
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ABSTRACT:
SUBMITTER: Mohideen F
PROVIDER: S-EPMC2753972 | biostudies-literature | 2008 Jun
REPOSITORIES: biostudies-literature
Publications
SUMO takes control of a ubiquitin-specific protease.
Mohideen Firaz F Lima Christopher D CD
Molecular cell 20080601 5
In this issue of Molecular Cell, Meulmeester et al. (2008) identify USP25 as a SUMO2/3-interacting protein and substrate. A USP25 SUMO interaction motif directs SUMO2/3 specificity, and SUMO modification diminishes USP25's ability to bind and degrade polyubiquitin chains. ...[more]
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