Comparative genomics of the eukaryotes.
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ABSTRACT:
SUBMITTER: Rubin GM
PROVIDER: S-EPMC2754258 | biostudies-literature | 2000 Mar
REPOSITORIES: biostudies-literature
Publications
Comparative genomics of the eukaryotes.
Rubin G M GM Yandell M D MD Wortman J R JR Gabor Miklos G L GL Nelson C R CR Hariharan I K IK Fortini M E ME Li P W PW Apweiler R R Fleischmann W W Cherry J M JM Henikoff S S Skupski M P MP Misra S S Ashburner M M Birney E E Boguski M S MS Brody T T Brokstein P P Celniker S E SE Chervitz S A SA Coates D D Cravchik A A Gabrielian A A Galle R F RF Gelbart W M WM George R A RA Goldstein L S LS Gong F F Guan P P Harris N L NL Hay B A BA Hoskins R A RA Li J J Li Z Z Hynes R O RO Jones S J SJ Kuehl P M PM Lemaitre B B Littleton J T JT Morrison D K DK Mungall C C O'Farrell P H PH Pickeral O K OK Shue C C Vosshall L B LB Zhang J J Zhao Q Q Zheng X H XH Lewis S S
Science (New York, N.Y.) 20000301 5461
A comparative analysis of the genomes of Drosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae-and the proteins they are predicted to encode-was undertaken in the context of cellular, developmental, and evolutionary processes. The nonredundant protein sets of flies and worms are similar in size and are only twice that of yeast, but different gene families are expanded in each genome, and the multidomain proteins and signaling pathways of the fly and worm are far more comp ...[more]
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