Ontology highlight
ABSTRACT:
SUBMITTER: Stivala CE
PROVIDER: S-EPMC2756537 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Stivala Craig E CE Zakarian Armen A
Organic letters 20090201 4
A stereoselective synthesis of the spiroimine fragment of spirolide C is described. The congested C7 and C29 tertiary and quaternary centers are constructed by a diastereoselective Ireland-Claisen rearrangement. The E ring is completed by means of an aldol cyclocondensation. Additional studies were preformed on the advanced intermediate to probe a future coupling strategy. ...[more]