Ontology highlight
ABSTRACT:
SUBMITTER: Pasutto F
PROVIDER: S-EPMC2756554 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
American journal of human genetics 20090917 4
Glaucoma, a main cause of blindness in the developed world, is characterized by progressive degeneration of retinal ganglion cells (RGCs), resulting in irreversible loss of vision. Although members of the neurotrophin gene family in various species are known to support the survival of numerous neuronal populations, including RGCs, it is less clear whether they are also required for survival and maintenance of adult neurons in humans. Here, we report seven different heterozygous mutations in the ...[more]