Ontology highlight
ABSTRACT:
SUBMITTER: Kampmann A
PROVIDER: S-EPMC2758385 | biostudies-literature | 2009 Feb
REPOSITORIES: biostudies-literature
Kampmann Andreas A Fernández Borja B Deindl Elisabeth E Kubin Thomas T Pipp Frederic F Eitenmüller Inka I Hoefer Imo E IE Schaper Wolfgang W Zimmermann René R
Molecular and cellular biochemistry 20081104 1-2
Arteriogenesis or collateral growth is able to compensate for the stenosis of major arteries. Using differential display RT-PCR on growing and quiescent collateral arteries in a rabbit femoral artery ligation model, we cloned the rabbit full-length cDNA of osteoglycin/mimecan. Osteoglycin was present in the adventitia of collateral arteries as a glycosylated protein without keratan sulfate side chains, mainly produced by smooth muscle cells (SMCs) and perivascular fibroblasts. Northern blot, Wes ...[more]