Ontology highlight
ABSTRACT:
SUBMITTER: Tikka-Kleemola P
PROVIDER: S-EPMC2759776 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Tikka-Kleemola P P Kaunisto M A MA Hämäläinen E E Todt U U Göbel H H Kaprio J J Kubisch C C Färkkilä M M Palotie A A Wessman M M Kallela M M
Cephalalgia : an international journal of headache 20090409 11
The effect of endothelin-1 and its receptors EDNRA and EDNRB in migraine with aura (MA) susceptibility is not established yet. We studied the association between the MA end-diagnosis and three migraine trait components and 32 single nucleotide polymorphisms (SNPs) capturing the variation of endothelin genes in 850 Finnish migraine patients and 890 non-migrainous individuals. The SNPs showing evidence of association were further studied in 648 German migraine patients and 651 non-migrainous indiv ...[more]