Ontology highlight
ABSTRACT:
SUBMITTER: Freilinger T
PROVIDER: S-EPMC3773912 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Freilinger Tobias T Anttila Verneri V de Vries Boukje B Malik Rainer R Kallela Mikko M Terwindt Gisela M GM Pozo-Rosich Patricia P Winsvold Bendik B Nyholt Dale R DR van Oosterhout Willebrordus P J WP Artto Ville V Todt Unda U Hämäläinen Eija E Fernández-Morales Jèssica J Louter Mark A MA Kaunisto Mari A MA Schoenen Jean J Raitakari Olli O Lehtimäki Terho T Vila-Pueyo Marta M Göbel Hartmut H Wichmann Erich E Sintas Cèlia C Uitterlinden Andre G AG Hofman Albert A Rivadeneira Fernando F Heinze Axel A Tronvik Erling E van Duijn Cornelia M CM Kaprio Jaakko J Cormand Bru B Wessman Maija M Frants Rune R RR Meitinger Thomas T Müller-Myhsok Bertram B Zwart John-Anker JA Färkkilä Markus M Macaya Alfons A Ferrari Michel D MD Kubisch Christian C Palotie Aarno A Dichgans Martin M van den Maagdenberg Arn M J M AM
Nature genetics 20120610 7
Migraine without aura is the most common form of migraine, characterized by recurrent disabling headache and associated autonomic symptoms. To identify common genetic variants associated with this migraine type, we analyzed genome-wide association data of 2,326 clinic-based German and Dutch individuals with migraine without aura and 4,580 population-matched controls. We selected SNPs from 12 loci with 2 or more SNPs associated with P values of <1 × 10(-5) for replication testing in 2,508 individ ...[more]