Ontology highlight
ABSTRACT:
SUBMITTER: Pu X
PROVIDER: S-EPMC2760382 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20090801 30
Unsymmetrically substituted allenes (1,2-dienes) are inherently chiral and can be prepared in optically pure form. Nonetheless, to date the allene framework has not been incorporated into ligands for asymmetric catalysis. Since allenes project functionality differently than either tetrahedral carbon or chiral biaryls, they may create complementary chiral environments. This study demonstrates that optically active, C(2)-symmetric allene-containing bisphosphine oxides can catalyze the addition of ...[more]